Tag Archives: medicine

Our complex addiction to medical spending – the New Yorker on the “pain-pills problem”

What we extravagantly spend on healthcare has become even more a pressing topic with the recent release of Medicare spending data – the most detailed dataset yet made public – and of course, the ongoing implementation of Obamacare. Last week, The New Yorker’s Rachel Aviv brought focus to a microlevel of medical spending: a doctor who thought he could save the most rejected of patients, and who now will spend up to 33 years in prison for “the unlawful distribution of controlled substances” that led to the deaths of several patients.

Unfortunately, Aviv’s article, titled “Prescription for Disaster; The heartland’s pain-pills problem” is behind a paywall. Here’s part of the abstract:

In 2005, the medical examiner in Wichita, Kansas, noticed a cluster of deaths that were unusually similar in nature: in three years, sixteen men and women, between the ages of twenty-two and fifty-two, had died in their sleep. In the hours before they lost consciousness, they had been sluggish and dopey, struggling to stay awake. A few had complained of chest pain. “I can’t catch my breath,” one kept saying. All of them had taken painkillers prescribed by a family practice called the Schneider Medical Clinic.

On September 13, 2005, Schneider arrived at work to find the clinic cordoned off with police tape…Agents from the Kansas Bureau of Investigation and the Drug Enforcement Administration led Schneider into one of the clinic’s fourteen exam rooms and asked him why he had been prescribing so many opioid painkillers.

He responded that sixty per cent of his patients suffered from chronic pain, and few other physicians in the area would treat them. The agents wrote, “He tries to believe his patients when they describe their health problems and he will believe them until they prove themselves wrong.” When asked how many of his patients had died, Schneider said that he didn’t know.

Aviv’s article is powerful, moreso because it managed to cover an impressive number of dysfunctional systems while detailing the very human aspect of failure. Dr. Schneider, as Aviv portrays him, is almost the archetype of the ideal heartland doctor. He was a manager of the local grocery’s meat department until he became inspired by how his hospital treated his daughter for pneumonia. He became the first in his family to graduate from college; his daughter tells Aviv that Schneider ‘was “never comfortable with the level of status” that came with the job.’

But Dr. Schneider’s humility and kind-heartedness ran into an ill-timed storm of palliative care research, social dysfunction, and market forces. After he opened his own practice, Dr. Schneider told Aviv that:

Pharmaceutical reps came in and enlightened me that it was O.K. to treat chronic pain because there is no real cure. They had all sorts of studies showing that the long-acting medications were appropriate.

Other doctors in Wichita sent their unwanted patients to Dr. Schneider. And “nearly a dozen sales representatives” would visit him each day, taking him out to meals and cluttering his office with branded gifts. I looked for Dr. Schneider’s name in ProPublica’s Dollars for Docs database, but his clinical work happened well before the wave of financial disclosures that came in 2007. Cephalon, which would later become notorious and criminally charged for illegally marketing its narcotics, was a frequent patron of Dr. Schneider’s. From Aviv’s report:

The company sent Schneider’s physician assistant to New York for an “Actiq consultants meeting”; it paid for her to stay at the W hotel and to ride a boat on the Hudson. In 2003, Schneider was sent to an Actiq conference in New Orleans, sponsored by Cephalon. He said that a specialist told him, “You could stick multiple Actiq suckers in your mouth and your rear end and you still wouldn’t overdose. It’s clinically impossible”

People shocked by the revelation of financial ties between doctors and drug companies often assume (sometimes without enough justification, in my opinion) that the doctors are traitors to the Hippocratic Oath and humanity. But Aviv’s report describes a doctor who is so Pollyannish that a prison guard chides him for talking to The New Yorker and Aviv: “you know she’s just going to tear you apart,” Schneider apparently confides to Aviv.

There’s more going on here than just the chase for money by the drug companies, or the naiveté/cravenness of the doctors who prescribe the drugs. There’s the huge issue of palliative care – how do we know whether patients really “need” painkillers? – and the pressure of politics, including the role of the D.E.A. and patient advocates, and of course, how much government should subsidize health care at all. There’s even the peripheral issue of electronic medical records and bureaucracy; Dr. Schneider’s clinic was so poorly managed that patients, who were rejected by one of the clinic’s doctors, would simply sign up with another doctor who worked at Schneider’s clinic, thanks to the clinic’s sloppy record keeping. It didn’t help that the clinic took in so many patients that “appointments were generally scheduled every ten minutes.”

It’s worth picking up a print copy – or even subscribing – just to read Aviv’s article on Dr. Schneider. It reveals the astonishingly heart-breaking complexity behind medical spending, and yet, even pushing the limits of the longform article format, it barely begins to describe the depth of that complexity.

Innovations in India’s Health Care

After reading this Bloomberg article, Heart Surgery in India for $1,583 Costs $106,385 in U.S., I couldn’t resist thinking about the end of Atul Gawande’s book, “Better: A Surgeon’s Notes on Performance“…cost comparisons to India inevitably bring up discussions along the lines of, “Well, just how good can their health care be?” Certainly, it’s hard to think of apples to apples metrics that would allow us to compare quality of care between the U.S. and India due to selection bias: patients in India who are able to go through heart surgery (and pay for it) may have a different health profile than the average American who undergoes that treatment.

Still, Gawande’s closing chapter in “Better” argues that even in relatively poor conditions, real, industry-changing innovation can occur due to necessity. In this final chapter, Gawande describes spending time in India as a visiting surgeon to see how innovative medical care was possible in comparatively squalid circumstances. The Nanded hospital he describes below serves 1,400 villages, about 2.3 million people, with just 9 surgeons (Gawande says that’d be comparable to the state of Kansas having 9 surgeons):

Among the many distressing things I saw in Nanded, one was the incredible numbers of patients with perforated ulcers. In my eight years of surgical training, I had seen only one patient with an ulcer so severe that the stomach’s acid had eroded a hole in the intestine. But Nanded is in a part of the country where people eat intensely hot chili peppers, and patients arrived almost nightly with the condition, usually in severe pain and going into shock after the hours of delay involved in traveling from their villages.

The only treatment at that point is surgical. A surgeon must take the patient to the operating room urgently, make a slash down the middle of the abdomen, wash out all the bilious and infected fluid, find the hole in the duodenum, and repair it. This is a big and traumatic operation, and often these patients were in no condition to survive it. So Motewar did a remarkable thing. He invented a new operation: a laparoscopic repair of the ulcerous perforation, using quarter-inch incisions and taking an average of forty-five minutes.

When I later told colleagues at home about the operation, they were incredulous. It did not seem possible. Motewar, however, had mulled over the ulcer problem off and on for years and became convinced he could devise a better treatment. His department was able to obtain some older laparoscopic equipment inexpensively. An assistant was made personally responsible for keeping it clean and in working order. And over time, Motewar carefully worked out his technique.

I saw him do the operation, and it was elegant and swift. He even did a randomized trial, which he presented at a conference and which revealed the operation to have fewer complications and a far more rapid recovery than the standard procedure. In that remote, dust-covered town in Maharashtra, Motewar and his colleagues had become among the most proficient ulcer surgeons in the world.

BTW, I whole-heartedly recommend Gawande’s “Better”, written in 2008. It extends upon his previous work, Checklist Manifesto, which was best known in its New Yorker incarnation.

The New York Times’ history of covering (up?) breast cancer

After Roger Ebert’s death last week, I picked up The Emperor of All Maladies: A Biography of Cancer, by Siddhartha Mukherjee, which was recommended during a discussion on how the war on cancer seemed hopeless. I’m not finished with the book yet, but I can already recommend it for being one of the best medical non-fiction books I’ve ever read.

The facts in Mukherjee’s “biography of cancer” seem to indicate that “no simple, universal, or definitive cure is in sight – and is never likely to be”, but Mukherjee also believes that medical science continues to make profound progress in understanding and treating cancer. And if anything, we might be farther along had we funded cancer research with the resources and commitment it requires.

After World War 2 drained interest and funding from cancer research, Mukherjee writes, “cancer again became the great unmentionable, the whispered-about disease that no one spoke about publicly.” As an example, he retells a story from the 2001 book, The Human Side of Cancer, in which a breast cancer activist describes being shunned by the New York Times:

In the early 1950s, Fanny Rosenow, a breast cancer survivor and cancer advocate, called the New York Times to post an advertisement for a support group for women with breast cancer. Rosenow was put through, puzzlingly, to the society editor of the newspaper. When she asked about placing her announcement, a long pause followed. “I’m sorry, Ms. Rosenow, but the Times cannot publish the word breast or the word cancer in its pages. “Perhaps,” the editor continued, “you could say there will be a meeting about diseases of the chest wall.” Rosenow hung up, disgusted.

The original source for Rosenow’s story – The Human Side of Cancer, by Dr. Jimmie C. Holland – has an upbeat coda:

However, [Rosenow and her friend] persisted, and their devoted efforts resulted in what is widely known as Reach to Recovery, a worldwide support program for women with breast cancer, administered today through the American Cancer Society.

Sixty-five years after the era of the Cleaver family, we’re still having serious debates over whether mothers should be allowed to breast-feed children in public. And Lady Justice herself was shamed about her wardrobe malfunction not too long ago. That the Times, still a stodgy paper today, would be too squeamish 65 years ago to print the word “breast” seems, well, self-evident. And so Rosenow’s story has been repeated in much of the major media coverage of Mukherjee’s book, including NPR, the Boston Globe, and even the New York Times itself.

What Ms. Rosenow described may have actually happened (it’s not like she or the Times society editor had Google or Lexis-Nexis back then), but a quick search of the New York Times digital archive shows that the Times had published articles about breasts and cancer throughout the 1950s.

For example, on September 24, 1950, the Times ran a story headlined “Movie Aids Cancer Detection:”

A color film designed to aid women in recognizing early signs of breast cancer is available for showings before Brooklyn women’s groups. Titled “Breast Self-Examination,” it was produced by the American Cancer Society and the National Cancer Institute of the United States Pubic Health Service.

Besides running notices of which local theaters were screening “Breast Self-Examination,” the Times also wrote several articles about the movie’s educational impact: “Cancer Film Saves Lives”, the Times reported on April 22, 1951. And, a year after the film’s introduction, the Times reported its success: 911,000 SAW CANCER FILM; Year’s Record Cited in Showing Self-Test for Women. And of course, the Times found fit to print the obligatory self-back-patting hug-your-newspaper-today feature: NEWSPAPER AID PRAISED; Cancer Experts Say Sufferers Gain by Care Publicity:

Newspapers and the radio were credited today with helping doctors fight cancer by causing sufferers to seek early treatment.

“There is no question but that the information made public by newspapers, radio, and other news services is making it possible for us to see patients with breast cancer earlier than ever before,” Dr. J. Elliott Scarborough, Jr., declared.

In fact, the breast cancer advice that the Times printed in 1952 doesn’t seem far removed from what you’d find in any contemporary medical column:

SELF-EXAMINATION URGED: Women Must Detect Early Stage of Breast Cancer, Doctor Says

If breast cancer is to be detected in its early stages, it is the women themselves who must do it…Dr. Haagensen said the breasts should be examined at least every two months to be reasonably sure they are free of cancer signs…Physicians, Dr. Haagensen said, should teach women self-examination.

Of course, cancer is a far more common topic of public concern and media coverage today. As Mukherjee himself points out, that’s because until relatively recently, humans generally didn’t live long enough to die from cancer. One of the earliest mentions of breast cancer in the Times archive occurs in 1852, in its column titled, Weekly Report of Deaths in the City and County of New York. Between January 10-17, the Times noted 324 deaths, the majority of them children. The top killers are diseases we rarely hear today: 54 deaths from consumption, 28 to convulsions, 20 to scarlet fever, 18 to “Dropsy in the head.” In contrast, “Cancer” and “Cancer of Breast” accounted for 1 death apiece. That cancer has become medicine’s public enemy number one is almost a sign of wealth and progress. In impoverished countries, cancer doesn’t even rank among the top 10 in causes of death.

If you’re interested in taking a depressing trip through medical history, type “cure for cancer” into the Times’ digital archive. You’ll find headlines from every decade – if not every one or two years – since 1852 touting a promising development in the fight against cancer:

If the war against cancer seems like an unending series of misguided schemes and false hope – much like our ongoing wars against terror, drugs, and poverty ‐ it’s because, like those wars, the enemy was never just one monolithic opponent that one kind of “weapon” (and lots of it) could ever defeat. So it’s fitting that the facts may be more complicated than they seem in Ms. Rosenow’s anecdote – because that’s the case with everything related to cancer. One of the most interesting things about Mukherjee’s attempt to write a “biography” of cancer is how, when the literary framing is inadequate for describing cancer, it serves only to more fully illuminate the scope of this war.